We Are Plant Based Formulators and Inventors

Cream of the Crop Therapeutics is focused on patent pending formulations and delivery methods for nasal consumption and pharmaceutical based topical delivery. We are not a licensed grower, processor or seller of cannabis products. We work with licensed producers and brands to expand product offerings in topical and nasal cannabinoid delivery. We invented the Nozzr™ Nose Budz for nasal cannabis consumption, a cannabis accessory.

Patent Pending Premier Nasal Cannabis Consumption Formulas and Devices

 

“Method of Plant Based Inhalation for the Treatment of Respiratory Viruses”, Sept. 2021

 

“Novel Nasal Adapter for Use With Aerosol and Vapor Delivery Devices”, Sept. 2022

The Cream of the Crop Therapeutic Co-Founder and CEO is a biologist and former respiratory specialist who worked in healthcare innovation for more than 20 years. Her Co-Founder (and husband) has a long, accomplished career in Canadian start-ups.

In 2014, she was diagnosed with Multiple Sclerosis (MS) and suffered from chronic pain and insomnia. The standard treatments offered to her weren’t effective, and her pain started to affect her quality of life.

Unable to find effective pain relief to treat her condition, she turned to the healing properties of cannabis to find solutions.

 

 

The Endocannabinoid System (ECS) and receptors are the targeted sites for our nasal and dermal products.

Formulations penetrate through mucosal and dermal barriers to deliver active ingredients.

Nasal inhalation:

  • increases bioavailability,
  • reduces cough,
  • and provides consumption options after dental work.

Dosed nasal sprays can be formulated for local symptom relief or systemic effects.

An overlooked opportunity for better medical acceptance of cannabis with an ability to offer rapid onset, dosing, predicable effects and duration.

Nasal References:

Cannabinoid Control of Olfactory Processes: The Where Matters. https://pubmed.ncbi.nlm.nih.gov/32316252/

Endocannabinoid-Mediated Neuromodulation in the Olfactory Bulb: Functional and Therapeutic Significance. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216281/

 

Cannabinoid Topicals:

  • penetrating bases with researched skin permeation,
  • 3.5% terpene and essential oil blends,
  • real world user feedback,
  • and lotions, oils and balms for joints and muscles, and skin.

Dermal formulations offer opportunity for pain and inflammation relief and an entry point for introducing cannabinoid medicine.

Skin References:

Cannabinoid Delivery Systems for Pain and Inflammation Treatment.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222489/.

 

Our largest organ, the skin has “cutaneous cannabinoid” receptors that are involved in skin homeostasis, barrier formation and regeneration.

Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System

https://pubmed.ncbi.nlm.nih.gov/30845666/.